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Epigenetics relates to the process wherein regulatory proteins have the ability to switch genes on and off in such a way that it may be passed on at some point…
What is the difference between Genetics and Epigenetics? Genetics is the study of heredity and the variation of inherited characteristics; epigenetics ...
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Japanese research group verified the presence of a protein modification that is a unique mark in human cell nucleus. This protein modification, Histone H4 lysine 20 acetylation (H4K20ac), was only discovered in plant cells and its existence in mammalian cells has been indirectly proven. Their study suggests that H4K20ac is associated with gene repression. This new discovery of H4K20ac may lead to further clarification of the mechanisms in disease progression.
http://knowingneurons.com/2013/06/13/your-brain-on-epigenetics/
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Methylation, commonly referred to as the “one-carbon metabolism”, is the transfer or formation of methyl (CH3) groups, such as MTHFR, COMT, and DNMT. Methylation frequently utilizes SAMe as a methyl donor. Methylation is fundamental for a variety of bodily structures and functions, including cell division, gene expression, early CNS development, immune cell differentiation, neurotransmitter biosynthesis and/or metabolism, histamine clearance, detoxification, hormone biotransformation, cellular energy metabolism, phospholipid synthesis, and the myelination of peripheral nerves, among other structures and functions. Among one of it’s most essential functions on structures, DNA methylation highly regulates a variety of epigenetic marks, making them substantially stable, such as the covalent bonds of X and Y chromosomes in men and women. Methylation occurs at CpG sites with DNMT enzymes. Moreover, DNA methylation can help regulate and/or manage other bodily structures and functions. Histone methylation, RNA methylation, and mitochondrial DNA methylation (miDNMT) can help induce or inhibit gene expression. Recent research studies have also demonstrated that these same enzymes may additionally be involved in demethylation. | Functional Medicine "Advancing The Medical Health Model"
How much control do we really have over our body's health? This question has intrigued and puzzled mankind since the beginning of time! The current biology laid down in most text books is known as 'genetic determinism', a persistent, pervasive idea that your genes decide your fate. Like all hypnoses, this idea is rather difficult to
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Hemochromatosis Ireland has launched a special national awareness for the blood disorder known as the Celtic Curse. National Hemochromatosis Day in Ireland will be June 7.
