Completed in 2011 in Amsterdam, The Netherlands. Images by Werner Huthmacher . Everything began with the arcade. The master plan specified that all the new buildings in the Oosterdokseiland development area near Amsterdam...
There are several bodywork techniques that can help heal the structural root causes of SIBO: integration, visceral mobilization to help adhesions and more!
Read about whole-body fascial and myofascial linkages to learn about Anatomy Trains. Discover how Tom Myers uses fascial planes to understand movement and stability.
Free essays, homework help, flashcards, research papers, book reports, term papers, history, science, politics
Image 10 of 55 from gallery of 'FitNation' Exhibition. San Francisco Federal Building / Morphosis / © Nic Lehoux
Nicolas Palopoli & Richard J Edwards Abstract Protein-protein interactions (PPI) between globular domains and Short Linear Motifs (SLiMs) play a crucial part in many biological processes. SLiMs are short stretches of 5 to 15 amino acids with high evolutionary plasticity that are usually found in disordered regions of proteins. Their role as ligands for molecular signalling, post-translational modifications and subcellular targeting has been increasingly studied over recent years, but experimental discovery of SLiMs remains a challenging task due to their small size and high degeneracy. As a consequence, computational tools for prediction and analysis of SLiMs are a valuable resource. We have previously developed SLiMFinder, a motif discovery tool that applies a model of convergent evolution to estimate the statistical significance of over-represented motifs with high specificity. Here, we aim to improve motif discovery by integrating SLiMFinder with methods that predict new domain-motif interactions directly from structural features in high-resolution 3D data. To this end we have developed “Query” SLiMFinder (QSLiMFinder), which uses knowledge of the interaction interface to constrain the motif search space and thereby increase search sensitivity. We have benchmarked QSLiMFinder using the Eukaryotic Linear Motif (ELM) database and simulated data. As expected, specific domain-motif interaction data can increase the power of de novo SLiM prediction from a set of proteins with a common PPI partner. We are now applying QSLiMFinder to large-scale analysis of public PPI and 3D structure data. Domain-motif interactions are predicted from structures in the protein data bank (PDB). QSLiMFinder then identifies patterns within the putative motif region that are over-represented in the other known PPI partners of the domain-containing protein. This will add crucial molecular details to the interactome.
ABSTRACT This research addresses the problem of dynamic structures seen from their struc-tural morphology and function in the field of architecture. Dynamic structures and specifically scissor syst…
ABSTRACT This research addresses the problem of dynamic structures seen from their struc-tural morphology and function in the field of architecture. Dynamic structures and specifically scissor syst…
Image 25 of 39 from gallery of Hulunbuir Hailar Airport / United Design U10 Atelier. Photograph by Ke Liu
ABSTRACT This research addresses the problem of dynamic structures seen from their struc-tural morphology and function in the field of architecture. Dynamic structures and specifically scissor syst…
Using natural circumstances to lessen the need for artificial or mechanical climate control is known as passive design Strategies. This means making the most of natural components by optimizing a building's layout, materials, openings, and orientation, which will ultimately improve environmental comfort. When these techniques are widely used, individual buildings become more ecologically friendly and their overall energy usage is drastically decreased.
Mass timber construction is changing how we fabricate and engineer wood, enabling new ways to design and construct buildings in the US.
111 East Grand is an exciting new addition to Des Moines' East Village. Its unique design utilizes mass timber construction.
* "The soul of man with all the streams of pure living water seems to dwell in the fascia of his body. When you deal with the fascia, you deal and do business with the branch offices of the brain,...
Completed in 2022 in Maisons-Alfort, France. Images by ©ArtBuild, ©Tristan Dechamps . AGORA is the cornerstone of a series of renovations to provide the National Veterinary School of Alfort (École Nationale Vétérinaire d'Alfort - EnvA)...
The way we build and the materials we use are changing, and we ain't seen nothin' yet.
Completed in 2012 in Dazaifu City, Japan. Images by Hiroyuki Kawano. One room (9m span) childcare room The nursery school built in Dazaifu, a city located near Fukuoka city, had to be extended for two classes in order...
The bracing systems are necessary for structures that are subjected to lateral loads due to earthquake, wind, etc. They help in minimizing the lateral
The degrees-of-freedom in a structure can be regarded as the possible components of displacements of the nodes including those at which some support conditions
Having procrastinated for the entire week, I had been up till 7 a.m. writing my English paper on monstrous Indian gods. And so when I […]
I’ve been spending some serious amounts of time this summer leading conversations around the country focused on the integration of social studies and literacy. And for the last few years, I…
Paving the way for mass timber construction in the United States, The Framework Project, LLC has just announced that it received approval for a building permit that will allow the country's first wood high-rise structure to be built.
© harry wei - erector house - 2013
Gutter Detail 1 curtain wall with integrated wood grille 2 steel structure 3 standing-seam metal roof 4 concealed gutter 5 steel outrigger system 6 wood deck soffit 7 aluminum fascia 8 wood veneer bulkhead
Has anyone ever talked to you about the fascia? Does it sound familiar? If you ever studied anatomy you may have possibly read about it. Maybe you heard about it from your chiropractor or massage therapist (I do like to talk about fascia from time to time). It
In a previous post I said I would go to into the metaphors within Wilber’s work combining my long-standing interest in his philosophical work with my new interest in metaphor theory. For the …
This should be a long post, but I am going to try and keep it as brief as possible. This post is more like an excerpt from the publication 'Structural
Image 10 of 12 from gallery of Wood Innovation Design Centre / Michael Green Architecture. Section
Some of these will surprise you, from being tired for optimal creativity to keeping a steady noise-level for your creative best.
Completed in 2013 in Venturada, Spain. Images by Alfonso Quiroga . As part of the Daoiz y Verlarde complex of former barracks the objective is to preserve the architecture; a representative sample of Madrid’s...
Image 6 of 29 from gallery of Fahrenheit DDB Advertising Offices / MASUNOSTUDIO. Photograph by Tomas Kjaervik
ScienceSoft outlines the architecture used in IoT development that enables process analysis based on sensor data and ensures control over the devices.
Deb Gulbrandson, PT, DPT is teaming up with Frank J Ciuba DPT, MS to create a new course called Osteoporosis Management: A Comprehensive Approach for Healthcare Professionals! This new course is launching remotely this July 25-26, 2020, and it emphasizes visual imagery cues which leads to enhanced performance for patients. Both course authors are t...
ABSTRACT This research addresses the problem of dynamic structures seen from their struc-tural morphology and function in the field of architecture. Dynamic structures and specifically scissor syst…
