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There are numerous diseases and conditions associated with being overweight.
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Background The resting metabolic rate (RMR) decrease, observed after an obesity reduction therapy is a determinant of a short-time weight regain. Thus, the objective of this study was to evaluate changes in RMR, and the associated hormonal alterations in obese patients with a very low-calorie ketogenic (VLCK)-diet induced severe body weight (BW) loss. Method From 20 obese patients who lost 20.2 kg of BW after a 4-months VLCK-diet, blood samples and body composition analysis, determined by DXA and MF-Bioimpedance, and RMR by indirect calorimetry, were obtained on four subsequent visits: visit C-1, basal, initial fat mass (FM) and free fat mass (FFM); visit C-2, − 7.2 kg in FM, − 4.3 kg in FFM, maximal ketosis; visit C-3, − 14.4 kg FM, − 4.5 kg FFM, low ketosis; visit C-4, − 16.5 kg FM, − 3.8 kg FFM, no ketosis. Each subject acted as his own control. Results Despite the large BW reduction, measured RMR varied from basal visit C-1 to visit C-2, − 1.0%; visit C-3, − 2.4% and visit C-4, − 8.0%, without statistical significance. No metabolic adaptation was observed. The absent reduction in RMR was not due to increased sympathetic tone, as thyroid hormones, catecholamines, and leptin were reduced at any visit from baseline. Under regression analysis FFM, adjusted by levels of ketonic bodies, was the only predictor of the RMR changes (R2 = 0.36; p
Background Sarcopenic obesity is a highly prevalent disease with poor survival and ineffective medical interventions. Mitochondrial dysfunction is purported to be central in the pathogenesis of sarc...
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Nous examinons ici en détail les différents signes qui peuvent indiquer un problème de foie.
A UCLA examine revealed in Brain Communications has recognized sex-specific mind alerts that affect weight problems improvement in males and women. By combining MRI information with medical options and private histories, researchers discovered variations in a number of mind networks related to youth adversity, psychological health high quality, and sensory stimulation experiences. The examine confirmed …
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Nous examinons ici en détail les différents signes qui peuvent indiquer un problème de foie.
A UCLA examine revealed in Brain Communications has recognized sex-specific mind alerts that affect weight problems improvement in males and women. By combining MRI information with medical options and private histories, researchers discovered variations in a number of mind networks related to youth adversity, psychological health high quality, and sensory stimulation experiences. The examine confirmed …
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Children and teenagers who are obese have different microorganisms living in the digestive tract than their lean counterparts, according to a new study.
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Is obesity only caused by eating too many calories and not moving enough? Researchers believe the environment may also be playing a role.
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Researchers from Germany and the US explained fat cells secrete ACE-2 receptors - known as the 'gateway' into the cells of the body.
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The point of this series is to depict certain struggles which the “mentally ill” people- as they are called, go through while living their lives as average Nigerians in a country that is not enligh…
