Saint Louve skincare is formulated in Melbourne with powerful active ingredients backed by clinical expertise to deliver advanced skincare formulations that improve skin health.

Dermatita seboreica am avut de pe la 12 ani. În ultimii 5 ani însă, după accidentul despre care v-am vorbit aici s-a accentuat foarte tare. Nu știu, e posibil să fie datorită corticosteroizilor și altor medicamente care mi-au fost administrate în perioada respectiva. Dermatita seboreica devenise atât de deranjantă, încât tot timpul trebuia să-mi verific […]

Our founder, Dr. Sarah Villafranco, shares her own experience with perioral dermatitis, and her top tips for healing perioral dermatitis naturally, including signs that perioral dermatitis is healing, and which products are best and worst for perioral dermatitis, both on your skin and in your home.

My Healing Journey One morning in early September I woke up with a few little red and fluid filled bumps around my mouth and nose area. I had initially assumed they were pimples, but within a few days the bumps only became larger in number, and had also begun to pop up on my chin near my mouth. I c

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There are eight types of B Vitamins and they all play important roles in skin health. Niacin(B3) improves skin elasticity and repairs skin damage, B5 helps w...

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Entre tantas preocupações que os pais têm com seus bebês, os problemas de pele fazem parte do top 10.

Phenol peel is among the riskiest treatments - but the results are showstopping. We’re here to explore its characteristics and answer: Is it worth it?

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An international team of scientists has identified at least 11 species of fish suspected to have land-walking abilities. The findings are based on CT scans and a new evolutionary map of the hillstream loach family, which includes the only living fish species caught in the act of walking: a rare,

Patch testing, prick and intradermoreactions with progesterone solubilized in sesame oil, and cytokine arrays found an increased expression of angiogenin, adiponectin, agouti-related protein, epidermal growth factor receptor (EGFR) and intercellular adhesion molecule 1 in lesional skin compared to uninvolved skin in AIPD. Based on the patient’s history and clinical features typical of an AIPD [3] , to demonstrate the presence of hypersensitivity to progesterone, we performed patch testing, prick and intradermoreactions with progesterone solubilized in sesame oil as described [2, 3] . All these investigations were performed during the follicular phase to avoid interference with endogenous progesterone. While patch and prick testing remained negative, intradermoreaction with micronized progesterone (at a concentration of 50 mg/ml diluted at 1/10 and 1/100 in sesame oil) elicited both an immediate and delayed reaction. The test at the 1/10 dilution triggered a very intense immediate reaction at the site of testing with a pruritic plaque of 6 cm in diameter associated with diffuse lesions (delayed reaction) on the trunk reproducing the usual relapsing dermatosis. The pruritic plaque persisted for 4 weeks. The obtained results were scored as positive provocation test. In contrast, testing with sesame oil alone triggered only a slight erythema consistent with a toxic reaction as previously described [2] . With the informed consent of the patient, we next performed cytokine arrays (Ray Bio Human Cytokine antibody array; C series 2000; panel 6.1, 7.1, 8.1; http://www.raybiotech.com/map_ all_m.asp#11) using tissue lysates prepared from normal and lesional skin specimens obtained from our patient. Among the 180 tested proteins, we found an increased expression of angiogenin, adiponectin, agouti-related protein, epidermal growth factor receptor (EGFR) and intercellular adhesion molecule 1 in lesional skin compared to uninvolved skin ( fig. 3 ). AIPD is a rare but characteristic entity, of which at least 70 cases have been described so far [1] . Its clinical presentation is extremely variable with erythematous, macular, papular and/or vesicular rashes [7–9] , palmoplantar dyshidrosis [2, 10] , erythemamultiforme-like lesion [2–4, 11, 12] , stomatitis [9] as well as urticaria [13, 14] , angioedema [6] and anaphylactic-like shock [7, 10, 15] . The lesions typically and constantly relapse during the luteal phase of the menstrual cycle. Besides cutaneous testing with progesterone as carried out in our case, other investigations useful for the diagnosis of AIPD include the intramuscular injection of medroxyprogesterone acetate [4, 8] , a vaginal progesterone provocation test [16] , search for circulating antibodies to progesterone [1, 2] , basophilic degranulation tests [4] , as well as the Elispot assay to identify progesterone-sensitive interferon -producing cells [11, 17] . The pathogenicity of AIPD is unclear. A model predicts an immune reaction to endogenous progesterone during the menstrual cycle [4] . This dermatosis, which is exclusively observed in women during child-bearing years, disappears completely with the menopause, an observation highlighting the importance of hormonal triggers. It has been suggested that previous progesterone