Nitric oxide is a powerful mediator in cell-to-cell communication and plays an essential function in various bodily processes.
As we age and our nitric oxide levels decrease, it's vital to supplement your diet with foods that boost nitric oxide and send your levels soaring.
Nitric oxide is a powerful mediator in cell-to-cell communication and plays an essential function in various bodily processes.
Acute dietary nitrate supplementation reduces resting blood pressure in healthy normotensives. This response has been attributed to increased nitric oxide bioavailability and peripheral vasodilation, although nitric oxide also tonically inhibits central sympathetic outflow. We hypothesized that acute dietary supplementation using beetroot (BR) juice would reduce blood pressure and muscle sympathetic nerve activity (MSNA) at rest and during exercise. Fourteen participants (7 men and 7 women, age: 25 ± 10 yr) underwent blood pressure and MSNA measurements before and after (165–180 min) ingestion of 70ml high- (~6.4 mmol ) BR or -depleted BR placebo (PL; ~0.0055 mmol ) in a double-blind, randomized, crossover design. Blood pressure and MSNA were also collected during 2 min of static handgrip (30% maximal voluntary contraction). The changes in resting MSNA burst frequency (−3 ± 5 vs. 3 ± 4 bursts/min, P = 0.001) and burst incidence (−4 ± 7 vs. 4 ± 5 bursts/100 heart beats, P = 0.002) were lower after BR versus PL, whereas systolic blood pressure (−1 ± 5 vs. 2 ± 5 mmHg, P = 0.30) and diastolic blood pressure (4 ± 5 vs. 5 ± 7 mmHg, P = 0.68) as well as spontaneous arterial sympathetic baroreflex sensitivity (P = 0.95) were not different. During static handgrip, the change in MSNA burst incidence (1 ± 8 vs. 8 ± 9 bursts/100 heart beats, P = 0.04) was lower after BR versus PL, whereas MSNA burst frequency (6 ± 6 vs. 11 ± 10 bursts/min, P = 0.11) as well as systolic blood pressure (11 ± 7 vs. 12 ± 8 mmHg, P = 0.94) and diastolic blood pressure (11 ± 4 vs. 11 ± 4 mmHg, P = 0.60) were not different. Collectively, these data provide proof of principle that acute BR supplementation can decrease central sympathetic outflow at rest and during exercise. Dietary supplementation may represent a novel intervention to target exaggerated sympathetic outflow in clinical populations. NEW & NOTEWORTHY The hemodynamic benefits of dietary nitrate supplementation have been attributed to nitric oxide-mediated peripheral vasodilation. Here, we provide proof of concept that acute dietary nitrate supplementation using beetroot juice can decrease muscle sympathetic outflow at rest and during exercise in a normotensive population. These results have applications for targeting central sympathetic overactivation in disease.
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Nitric oxide - Doctors are saying it's one of the most important molecules in our bodies. Don't miss this lineup of medical experts and what they have to say about nitric oxide, how it works and how to produce more of it.
Nitric oxide is a powerful mediator in cell-to-cell communication and plays an essential function in various bodily processes.
Athletes should eat many foods high in nitrates, like beets, lettuce, arugula, spinach & celery. They increase oxygen supply to the muscles!
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Written by a truly global team of researchers from Europe, Asia and the Americas with strong ties to agricultural research centers and the agrochemical industry, this ready reference and handbook focuses on the role of nitric oxide signaling in plant defense systems against pathogens, parasites and environmental stress response.This is one of the first…
Low nitric oxide is a serious health problem. Here are 15 things you can do (and shouldn't do) to boost nitric oxide. Get healthy. Live a life of strength and vitality!
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Nitric Oxide Testing What is Nitric Oxide Testing? Our nitric oxide test is a simple, non-invasive method to determine if you are getting enough essential nitric oxide from the foods you eat. Nitric oxide plays a key role in keeping your blood vessels (including the ones in your heart and…
