Download scientific diagram | Research framework based on the Anishinaabe/ Cree Medicine Wheel. Holistic health involves physical, mental, emotional, and spiritual dimensions (center). Research processes guided by these principles are indicated in boxes. Researchers must make iterative journeys around the wheel to remain ethically engaged with community (blue text). Initial concerns of collaborators are identifi ed in circles. from publication: Methodology Matters: Designing a Pilot Study Guided by Indigenous Epistemologies | Indigenous individuals and communities have experienced historic and ongoing negative interactions with Western health care and biomedical research. To rebuild trust and mitigate power structures between researchers and Indigenous peoples, researchers can adopt Indigenous... | Indigeneity, Epistemology and Pilot Projects | ResearchGate, the professional network for scientists.