3 things you didn’t know about PMDD ☽ It affects an estimated 5.5% of women and Assigned female at birth Individuals of reproductive age. ☽ The Luteal phase (or last two weeks) of the cycle can be a roller coaster of emotions for humans who suffer from PMDD often filled with lethargy, low libido, anxiety, disassociation and even suicidal thoughts. ☽ Hormonal birth control often aggravates PMDD symptoms because individuals with PMDD are often sensitive to synthetic hormones.