Madeline Usher is Roderick Usher's driven and ambitious twin sister, and the brains behind Fortunato Pharmaceuticals. Madeline picks up the slack for her brother when he falters, but would step over him if she had to, regardless of the love she has for Roderick. She is described as a genius that appears five times in a century. She works on an Artificial Intelligence programme, using Lenore's personality as a base for beta testing. She also developed a prediction programme – at first predicting